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Treatment and prevention involve eating meat, fish, and dairy products or foods fortified with B12, like some breakfast cereals and breads
Oral administration faces hepatic first-pass metabolism, reducing bioavailability to approximately 4050% of subcutaneous routes, but offers convenience for longer-term studies where daily injections create compliance challenges
Any preparation, aliquoting, solvent compatibility review, or research recordkeeping should be carried out according to established local compliance standards and documented laboratory workflows
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Evidence boundary The published trial record describes safety more clearly than efficacy
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